There is no definitive answer to this question, as it depends on the particular story you are looking to tell in your memoir. However, some possible hooks for a memoir could be:
-A life-changing event that alters the course of your life
-A unique or interesting profession or lifestyle
-Overcoming adversity or a difficult challenge
Ultimately, the most important thing is to choose a hook that will grab readers' attention and make them want to continue reading your story.