What is the most popular children's book? What makes it so popular? What are some of the themes and characters that make it so beloved?The most famous children's book is probably "The Cat in the Hat" by Dr. Seuss. It is a classic and beloved by children and adults alike. The book is full of fun rhymes and whimsical illustrations, making it a great read for young readers. The story follows a mischievous cat who turns a boring rainy day into an adventure with the help of Thing 1 and Thing 2. The themes of friendship, imagination, and problem-solving make the book a timeless classic.