Yes indeed, Amazon Prime has a plethora of great series to choose from.
If you're looking for comedies, check out Red Oaks and Forever. Red Oaks is a lighthearted look at a young man working as an assistant tennis pro at an exclusive country club, while Forever is an episodic dramedy following an eccentric married couple who never seem to stay in one place for too long.
For drama, Transparent and The Man in the High Castle are particularly good. Transparent follows a family dealing with the ramifications when one of its members comes out as transgender, while The Man in the High Castle is an alternate history of World War II in which the Axis Powers won.
If you're a fan of sci-fi, then you should check out The Expanse and The Tick. The Expanse follows a police detective who is investigation a case that could yield devastating repercussions for humanity, while The Tick follows a strange, mysterious, and superhuman figure who appears to be a superhero in a world full of superheroes.
Finally, if you're looking for something a little darker, check out Hand of God and Sneaky Pete. Hand of God is a psychological, supernatural thriller about a judge whose faith is tested when he realizes he may be hearing the voice of God, while Sneaky Pete follows a con artist posing as his recently-deceased cellmate to escape from the mob.
Overall, Amazon Prime has some great series worth watching, and there's something for every mood and genre. Enjoy!